Diabetes and Obesity

2019 July

 

 

2018 Feb

 

 

2017 July

BREAKING NEWS: Editors’ Picks

Association of Modifiable Risk Factors in Young Adulthood With Racial Disparity in Incident Type 2 Diabetes During Middle Adulthood. JAMA, 2017 Dec.

Black people have double the rate of diabetes compared to whites by midlife. Obesity is the driven factor.

Body weight homeostat that regulates fat mass independently of leptin in rats and mice. PNAS, 2017 Dec

New evidence for the existence of an internal body weight sensing system, which could lead to a better understanding of the causes of obesity as well as new anti-obesity drugs.

Anti-stress compound (FKBP51-protein inhibitors) reduces obesity and diabetes. Nature Communications, 2017 Dec

True impact of global diabetes epidemic is vastly underestimated. Nature Reviews Endocrinology, 2016 July.

There may be more than 100 million people with diabetes globally than previously thought. The prevalence of global diabetes has been seriously underestimated by at least 25 per cent, the paper suggests.

Association Between Long-Term Exposure to Air Pollution and Biomarkers Related to Insulin Resistance, Subclinical Inflammation and Adipokines. Diabetes, 2016 Sept;

Exposure to air pollution at the place of residence increases the risk of developing insulin resistance as a pre-diabetic state of type 2 diabetes.

The Major Link Between Obesity and Diabetes. From Dr. Louis Venter. May 6, 2016

Leptin plays a direct role in cardiovascular disease in obesity. Circulation, October 7, 2015

While high levels of the satiety hormone leptin don’t help obese individuals lose weight, they do appear to directly contribute to their cardiovascular disease.

Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth. PNAS, 2015 Sept

As obesity rates for pregnant women continue to climb, scientists have discovered that increasing a specific hormone during pregnancy can reduce or eliminate the chances that the baby will become obese as well.

High dietary fiber intake linked to health promoting short chain fatty acids. Gut, September 29, 2015

Eating a lot of fibre-rich foods, such as fruit, vegetables, and legumes–typical of a Mediterranean diet–is linked to a rise in health promoting short chain fatty acids (SCFAs), which include acetate, propionate, and butyrate, are produced by bacteria in the gut during fermentation of insoluble fibre from dietary plant matter. SCFAs have been linked to health promoting effects, including a reduced risk of inflammatory diseases, diabetes, and cardiovascular disease.