BMJ Open. 2016 Nov 18;6(11):e010927.

Retrospective analysis of age-adjusted body mass index among pre-pregnant women in the Lithuanian urban area during three decades.

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The incidence of overweight and obesity increased worldwide progressively over the decades, suggesting that a rising trend in prevalence is not a recent phenomenon.1 2 Lately, there is a growing body of evidence about the stabilization of obesity epidemic or slowing down of body mass index trend increases.35 A declining trend in obesity prevalence is documented more commonly among children, but stabilisation in the prevalence of excess weight is predicted in adults as well.46 Unfortunately, evidence shows that pre-pregnancy obesity prevalence continues to increase and varies by race-ethnicity and maternal age.78 There are studies reporting that the incidence of maternal obesity at the beginning of pregnancy is also increasing and accelerating and that obesity among pregnant women is becoming one of the most important women’s health issues for this decade.9 Maternal obesity can lead to various negative outcomes for both mothers and their offspring. It has been reported to be associated with an increased risk of gestational diabetes, hypertension, pre-eclampsia, stillbirth, fetal macrosomia and caesarean section.1011

We have conducted gestational diabetes long term consequences study, which survey the influence of gestational diabetes and obesity during pregnancy on the health of women and their offspring. One of the objectives of the research was to determine the prevalence of overweight and obesity among young women in Lithuanian urban region. We reviewed antenatal records of 2896 pregnant women who received maternity care services in 1987-1989, 1996-1997 and 2007-2010 in two outpatient departments of Kaunas city (Lithuania). The result is encouraging with the decreasing trend of overweight and obesity prevalence among pre-pregnant women in the Lithuanian urban area during 3 decades.

We also examined 137 women who had gestational diabetes previously (15 years ago or earlier) to evaluate the long-term consequences. Carbohydrate metabolism, dyslipidemia, adipocytokines, genetic evaluation was set for the subjects. We evaluated the data on children born after pregnancies complicated by gestational diabetes and their siblings as well. It will submit supplementary information of gestational diabetes long-term consequences to the offspring. Additional data analyzes will be submitted in publications.



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