2019
1. Verteporfin blocks Clusterin which is required for survival of gastric cancer stem cell by modulating HSP90 function. Int J Biol Sci. 2019 Jan 1;15(2):312-324.
3. Safety and Efficacy of the Intravenous Infusion of Umbilical Cord Mesenchymal Stem Cells in Patients With Heart Failure: A Phase 1/2 Randomized Controlled Trial (RIMECARD Trial [Randomized Clinical Trial of Intravenous Infusion Umbilical Cord Mesenchymal Stem Cells on Cardiopathy]). Circ Res. 2017 Oct 27;121(10):1192-1204.
5. Neuronal and Glial Differentiation of Human Neural Stem Cells Is Regulated by Amyloid Precursor Protein (APP) Levels. Mol Neurobiol. 2019 Feb;56(2):1248-1261.
2. Targeting Cancer Stem Cell Redox Metabolism to Enhance Therapy Responses. Semin Radiat Oncol. 2019 Jan;29(1):42-54.
4. Anti-inflammatory compound curcumin and mesenchymal stem cells in the treatment of spinal cord injury in rats. Acta Neurobiol Exp (Wars). 2018;78(4):358-374.
6. Pathological ASXL1 Mutations and Protein Variants Impair Neural Crest Development. Stem Cell Reports. 2019 May 14;12(5):861-868.
2018
1. Slow-Myofiber Commitment by Semaphorin 3A Secreted from Myogenic Stem Cells. Stem Cells. 2017 Jul;35(7):1815-1834.
3. Ultrasmall, water dispersible, TWEEN80 modified Yb:Er:NaGd(WO4)2 nanoparticles with record upconversion ratiometric thermal sensitivity and their internalization by mesenchymal stem cells. Nanotechnology. 2017 May 5;28(18):185101.
5. Substrate Curvature Restricts Spreading and Induces Differentiation of Human Mesenchymal Stem Cells. Biotechnol J. 2017 Sep;12(9).
2. Dynamic regulation of Nanog and stem cell-signaling pathways by Hoxa1 during early neuro-ectodermal differentiation of ES cells. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):5838-5845.
4. Intra-Articular Injection of Human Synovial Membrane-Derived Mesenchymal Stem Cells in Murine Collagen-Induced Arthritis: Assessment of Immunomodulatory Capacity In Vivo. Stem Cells Int. 2017;2017:9198328.
2017 Feb
1. A role for mitotic bookmarking of SOX2 in pluripotency and differentiation. Genes Dev. 2016 Nov 15;30(22):2538-2550. 3. Intravenous vs intraperitoneal transplantation of umbilical cord mesenchymal stem cells from Wharton’s jelly in the treatment of streptozotocin-induced diabetic rats. Diabetes Res Clin Pract. 2016 Nov;121:102-111. 5. Protein S Regulates Neural Stem Cell Quiescence and Neurogenesis. Stem Cells. 2017 Mar;35(3):679-693. 7. Transduction Function of a Magnetic Nanoparticle TMADM for Stem-Cell Imaging with Quantum Dots. Anal Sci. 2017;33(2):143-146. 9. Role of extracellular vesicles in the interaction between epithelial and mesenchymal cells during oviductal ciliogenesis. Biochem Biophys Res Commun. 2017 Jan 29;483(1):245-251. 2. Epigenetic programming of adipose-derived stem cells in low birthweight individuals. Diabetologia. 2016 Dec;59(12):2664-2673. 4. Photobiomodulation Therapy Promotes Expansion of Epithelial Colony Forming Units. Photomed Laser Surg. 2016 Nov;34(11):550-555. 6. Quiescence Preconditioned Human Multipotent Stromal Cells Adopt a Metabolic Profile Favorable for Enhanced Survival under Ischemia. Stem Cells. 2017 Jan;35(1):181-196. 8. PS1/γ-Secretase-Mediated Cadherin Cleavage Induces β-Catenin Nuclear Translocation and Osteogenic Differentiation of Human Bone Marrow Stromal Cells. Stem Cells Int. 2016;2016:3865315.
BREAKING NEWS: Editors’ Picks
Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature, 2018 Jan;
How alcohol damages DNA in stem cells, helping to explain why drinking increases the risk of cancer
Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects. BMC Medicine, 2017 Feb.
Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor.
Stem cells used to regenerate the external layer of a human heart. Nature Biomedical Engineering, 2017 Jan.
Long-term self-renewing human epicardial cells generated from pluripotent stem cells under defined xeno-free conditions.
Deep Learning predicts hematopoietic stem cell development. Nature Methods, 2017 Feb.
Deep Learning is generating more and more public awareness. Scientists have now used it to determine the development of hematopoietic stem cells in advance: they describe how their software predicts the future cell type based on microscopy images.
Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome. Nature Communications, 2016 Dec
Researchers have developed a synthetic version of a cardiac stem cell, offering therapeutic benefits comparable to those from natural stem cells and could reduce some of the risks associated with stem cell therapies. Additionally, these cells have better preservation stability and the technology is generalizable to other types of stem cells.
Functional human liver cells grown in the lab. Nature Biotechnology, November 26, 2015
This groundbreaking development could help advance a variety of liver-related research and applications, from studying drug toxicity to creating bio-artificial liver support for patients awaiting transplantations.